Evaluation of Therapeutic Efficacy of Pulsed Dye Laser in Facial Melanocytic Junctional Nevi; A Single-arm Non-randomized Clinical Trial

Document Type : Brief Report


1 Student Research Committee, Baqiyatallah University of Medical Science, Tehran, Iran

2 Trauma Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran

3 Department of Epidemiology and Biostatistics, Faculty of Health, Baqiyatallah University of Medical Sciences, Tehran, Iran.

4 Department of Dermatology, Baqiyatallah University of Medical Sciences, Tehran, Iran


Introduction: Mostly located in the dermo-epidermal junction, junctional nevus is a type of melanocytic nevi which is consisted of nevoid cells. A variety of treatment methods have been introduced so far for facial junctional nevi; however, they may be associated with scars. We aimed to evaluate the therapeutic efficacy of pulsed dye laser (PDL) and aesthetic improvement in patients with melanocytic junctional nevi.
Methods: This quasi-experimental study was conducted between January and April 2019 in Baqiyatallah dermatology clinic. We included patients with melanocytic junctional nevi in neck and face equal to or less than 10 mm as well as those between 15 and 30 years of age. Before intervention, we took a photograph of Nevus. Then this photograph was repeated at the beginning of each session and one month after the last session of laser therapy. The laser parameters for treatment were set to 10 joules energy and pulse width of 3 milliseconds. We asked a non-participant faculty member to determine the rate of improvement by visual analogue scale (VAS).
Results: Eventually, 37 patients (120 nevi in 25 male and 12 female) were analyzed. Male patients had a mean age of 24.9±2.3 years and this was 23.4±1.9 for female individuals. Four (10.8%) patients experienced an improvement of less than 50%, 10(27.1%) patients had an improvement rate between 50% and 75% and 23(62.1%) patients had improvements more than 75%.
Conclusion: it seems that PDL may efficiently and sufficiently improve the facial junctional nevus with no side effects.


Main Subjects

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