Document Type : Case Report
Oncosurgeon, Kowsar Hospital
Resident in Radiation Oncologist, Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran
Pathologist, Kowsar Hospital
General Practitioner, Kowsar Hospital
Assistant professor in Radiation Oncologist, Radiation Oncology Department, Shiraz University of Medical Sciences, Shiraz, Iran
Asistant professor in Radiation Oncology, Breast Diseases Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Assistant Professor in radiation Oncology, Department of Radiation oncology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Introduction: Dermatofibrosarcoma protuberans (DFSP) is a rare tumor and has a slow-growing behavior. Presentation is nonspecific, and diagnosis is made after the operation and pathologic examination. The most common sites of this tumor are the trunk, head and neck, and extremities. Case Presentation: We report a 42-year-old woman presenting with a breast mass and positive history of breast cancer in her mother. Pre-operation biopsy showed phyllodes tumor. After wide excision of the mass, the pathology report confirmed the DFSP diagnosis. Apart from surgery, she received no adjuvant treatment (chemotherapy, radiotherapy, or hormone therapy). The patient has not experienced recurrence since then. Conclusion: According to the rarity and high rate of recurrence of breast DFSP, it should not be missed as a differential diagnosis of breast masses. Taking a multidisciplinary approach and using proper diagnosis and treatment methods can improve the outcome.
- Wide local excision is the most used treatment method for breast Dermatofibrosarcoma protuberans (DFSP) cases.
- In the breast DFSP, adjuvant therapy (e.g., radiotherapy, chemotherapy) is not required in the operable cases without margins.
- The key feature of DFSP is the high rate of recurrence; thus, morbidity occurs in some cases. Developing and applying proper diagnostic and treatment methods can improve the outcomes.